长期从事生物化工，生物育种技术与装备及其应用，发酵工程，微流控微生物培养技术与装备及其应用，健康工程，酶工程，多糖生物医药创制，天然活性肽等方面的研究。其中，多糖裂解酶工程技术、生物育种技术与装备、降尿酸大鲵软骨活性肽技术已进入产业化应用，取得了显著的社会、经济和环境效益。已在国际、国内学术刊物发表论文300余篇，合作著书8本，译著教材2部，英文专著1部，获得发明专利100余件，其中5件国际专利，10余件专利转化应用。至今获得省部级奖4项，2014-2018年连续入选爱思唯尔高被引学者。作为清华-东工大等多个研究生联合培养项目负责人，为国际化教育发展做出贡献。
● 教育与工作经历
1981.09-1985.07 华南工学院应用化学系本科 理学学士
1985.11-1986.07 国家教委出国预备研究生(华南工学院)
1986.10-1989.03 日本宇都宫大学大学院应用化学专业 工学硕士
1989.03-1992.03 日本东京工业大学大学院化学工程专业 工学博士
1992.04-1998.02 日本东京工业大学生命理工学部 助理教授
1997.05-1997.07 中国科学院化工冶金研究所国家生化工程重点实验室客座研究员
1998.03-2001.07 日本横滨国立大学工学部物质工学专业 讲师、副教授
1999.07-1999.10 清华大学化工系客座教授
2000.09-现在 清华大学化工系教授、百名人才工程入选者
2002.09-现在 担任清华大学化工系生物化工研究所所长
2012-2022.01 工业生物催化教育部重点实验室副主任
2009.03-2018.06 清华大学 化工系副系主任
2019.06-现在 清华大学深圳国际研究生院 生物医药与健康工程研究院教授，常务副院长
● 研究领域
主要研究方向包括生物化工，生物育种技术与装备及其应用，发酵工程，微流控微生物培养技术与装备及其应用，健康工程，酶工程，多糖生物医药创制，天然活性肽等方面的研究。长期坚持以问题为导向的工程科学思路，形成了生物化工基础和应用研究、技术和装备并重的学术特色，通过基础研究支撑应用转化，成功实现了科研成果的产业化应用。
● 开设课程
环境生物技术（研究生专业课，32学时，主讲人）
生物工程前沿进展（研究生专业课，16学时，主讲人）
新生研讨课（本科生，16学时，主讲人）
● 主要学术与社会任职
曾任第十、十一、十二届全国政协委员，担任中国侨联委员，北京市侨联副主席，清华大学侨联主席，北京市侨联特聘专家。
担任中国化工学会生物化工专业委员会技术委员会委员、中国化工学会医药化工专业委员会副主任委员、中国化工学会第四十届理事会理事、中国化工学会第四十届国际学术交流工作委员会副主任委员及中日交流工作委员会主任、中国化工学会医药化工专业委员会副主任委员、中国生物发酵产业协会第三届理事会理事、中国生物发酵产业协会微生物育种分会副理事长、中国生物发酵产业标准化技术委员会第二届委员会委员、中国生化制药工业协会第二届专家委员会委员，中国生化制药工业协会多糖类药物分会专家委员会主任、中国食品药品监督管理总局特殊医学用途配方食品和特殊膳食抽检监测牵头分析专家委员会委员、皮肤健康产业中国科技联盟副理事长和第一届轮值主席。
担任《Journal of Future Foods》科学主编，《Biochemical Engineering Journal》副主编，《合成生物学》、《中国酿造》、《食品科学》、《生物工程学报》、《Food Sciences and Human Wellness》、《Enzymatic and Microbial Technology》、《Journal of Biotechnology》、《Industrial Biotechnology》、《Food Chemistry Advances》、《Frontiers in Bioengineering and Biotechnology》、《Microorganisms》编委。曾担任《Journal of Bioscience and Bioengineering》、《Journal of Molecular Catalysis B: Enzymatic》、《Journal of Biological Engineering》、《食品与生物技术》编委。
● 代表性论文
1. Zhidan Liu, Buchun Si, Jiaming Li, Jianwei He, Chong Zhang*, Yuan Lu, Yuanhui Zhang and Xin-Hui Xing*, Bioprocess engineering for biohythane production from low-grade waste biomass: technical challenges towards scale up. Current Opinion in Biotechnology, 50, 25-31 (2018)
2. Lan-Yu Cui, Shan-Shan Wang, Chang-Ge Guan, Wei-Fan Liang, Zheng-Lian Xue, Chong Zhang,* and Xin-Hui Xing*, Breeding of Methanol-Tolerant Methylobacterium extorquens AM1 by Atmospheric and Room Temperature Plasma Mutagenesis Combined With Adaptive Laboratory Evolution. Biotechnology Journal, 1700679 (2018)
3. Yang Ji, Yuan Lu, Yishu Yan, Xinxin Liu, Nan Su, Chong Zhang, Shengli Bi*, Xin-Hui Xing* Design of Fusion Proteins for Efficient and Soluble Production of Immunogenic Ebola Virus Glycoprotein in Escherichia coli. Biotechnology Journal, 1700627 (2018)
4. Wenming Zhu, Yang Ji, Yi Wang, Dong He, Yishu Yan, Nan Su, Chong Zhang and Xin-Hui Xing*, Structural characterization and in vitro antioxidant activities of chondroitin sulfate purified from Andrias davidianus cartilage. Carbohydrate Polymers, 196, 398-404 (2018)
5. Tianmin Wang##, Changge Guan##, Jiahui Guo, Bing Liu, Yinan Wu, Zhen Xie, Chong Zhang*, and Xin-Hui Xing, Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance. Nature Communications, 9, 2475 (2018)
6. Zhou YK (Zhou, Yikang), Li G (Li, Gang), Dong JK (Dong, Junkai), Xing XH (Xing, Xin-hui), Dai JBA (Dai, Junbiao), Zhang C (Zhang, Chong)*, MiYA, an efficient machine-learning workflow in conjunction with the YeastFab assembly strategy for combinatorial optimization of heterologous metabolic pathways in Saccharomyces cerevisiae. Metabolic Engineering, 47, 294-302 (2018)
7. Jiahui Guo##, Tianmin Wang##, Changge Guan, Bing Liu, Cheng Luo, Zhen Xie, Chong Zhang*, Xin-Hui Xing, Improved sgRNA design in bacteria via genome-wide activity profiling. Nucleic Acid Research, 46(14), 7052-7069 (2018)
8. Hou Ji-Lun, Zhang Xiao-Yan, Wang Gui-Xing, Sun Zhao-Hui, Du Wei, Zhao Ya-Xian, Si Fei, Wang Li-Yan, Xing Xin-Hui*, Wang Yu-Fen*, Novel breeding approach for Japanese flounder using atmosphere and room temperature plasma mutagenesis tool. BMC Genomics, 20: 323 (2019)
9. Chunxuan Ma, Zhenglin Tan, Ying Lin, Shuangyan Han, Xin-Hui Xing, Chong Zhang*, Gel-microdroplet-based high throughput screening for directed evolution of xylanase-producing Pichia pastoris. Journal of Bioscience and Bioengineering, 128(6): 662-668 (2019)
10. Yi-Fan Xing, Dong He, Yi Wang, Wen Zeng, Chong Zhang, Yuan Lu, Nan Su, Yan-Hua Kong and Xin-Hui Xing*, Chemical Constituents, Biological Functions and Pharmacological Effects for Comprehensive Utilization of Eucommia ulmoides Oliver. Food Science and Human Wellness, 8(2), 177-188 (2019)
11. Tan, ZL (Tan, Zheng Lin); Zheng, X (Zheng, Xiang); Wu, YA (Wu, Yinan); Jian, XJ (Jian, Xingjin); Xing, XH (Xing, Xinhui); Zhang, C (Zhang, Chong)*, In vivo continuous evolution of metabolic pathways for chemical production. Microbial Cell Factory, 18: 82 (2019)
12. 陈政霖, 马春玄, 邢新会, 张翀*，微生物微培养系统研究现状与展望。生物工程学报， 27(1): 1-6 (2019)。
13. 周雪，王怡，何东，曾文，张翀，薛正莲，邢新会*，口服肝素与小鼠肠道菌群的相互作用过程。生物工程学报，35(9):1736-1749（2019）。
14. 张雪，吴亦楠，马飞，王立言，张翀，李和平，邢新会*，ARTP 诱变技术在食品和饲料加工生物催化剂改造中的应用进展。生物产业技术，2019年3月号，13-24 （2019）
15. Huimin Zhang; Yajing Meng; Yanli Wang; Qingwu Zhou; Anjun Li; Guoying Liu; Jingxin Li; Xin-Hui Xing*, Prokaryotic Communities in Multidimensional Bottom-Pit-Mud from Old and Young Pits Used for the Production of Chinese Strong-Flavor Baijiu. Food Chemistry, 312: 126084 (2020)
16. Dong He, Yi Wang, Jun Lin, Yi-Fan Xing, Wen Zeng, Wen-Ming Zhu, Nan Su, Chong Zhang, Yuan Lu, and Xin-Hui Xing*, Identification and characterization of alcohol-soluble components from wheat germ-apple fermented by Lactobacillus sp. capable of preventing ulcerative colitis of dextran sodium sulfate-induced mice. Journal of Functional Foods, 64, 103642 (2020)
17. Wang, TM (Wang, Tianmin)#,* ; Zheng, X (Zheng, Xiang)# ; Ji, HN (Ji, Haonan); Wang, TL (Wang, Ting-Liang); Xing, XH (Xing, Xin-Hui); Zhang, C (Zhang, Chong)*， Dynamics of transcription-translation coordination tune bacterial indole signaling. Nature Chemical Biology, 16, 440-449 (2020)
18. Yang Ji#, Yi Wang#, Wen Zeng, Xiang Mei, Shanshan Du, Yishu Yan, Jie Hao, Zhenqing Zhang, Yuan Lu, Chong Zhang, Jun Ge and Xin-Hui Xing*. A heparin derivatives library constructed by chemical modification and enzymatic depolymerization for exploitation of non-anticoagulant functions. Carbohydrate Polymers, 249, 116824 (2020)
19. Liyan Wang# Hongxin Zhao#, Dong He, Yinan Wu, Lihua Jin, Guo Li, Nan Su, Heping Li* and Xin-Hui Xing*, Insights into the molecular-level effects of atmospheric and room-temperature plasma on mononucleotides and single-stranded homo- and hetero-oligonucleotides. Scientific Reports, 10:14298 (2020)
20. Xingjin Jian#, Xiaojie Guo#, Jia Wang, ZhengLin Tan, Xin–Hui Xing, Liyan Wang* and Chong Zhang*, Microbial microdroplet culture system (MMC): an integrated platform for automated, high–throughput microbial cultivation and adaptive evolution. Biotechnology and Bioengineering, 117 (6), 1724-1737 (2020)
21. Dong He#, Xue Peng#, Yi-Fan Xing, Yi Wang, Wen Zeng, Nan Su, Chong Zhang, Dian-Nan Lu*, Xin-Hui Xing*, Increased stability and intracellular antioxidant activity of chlorogenic acid depend on its molecular interaction with wheat gluten hydrolysate. Food Chemistry, 325：12687 (2020)
22. Li, JM (Li, Jiaming); He, JW (He, Jianwei); Si, BC (Si, Buchun) ; Liu, ZD (Liu, Zhidan) *; Zhang, C (Zhang, Chong)*; Wang, YX (Wang, Yuxin); Xing, XH (Xing, Xin-hui)*, A pilot study of biohythane production from cornstalk via two-stage anaerobic fermentation. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY,45 (56),31719-31731 (2020)
23. Jia Wang, Xinjing Jian, Xin-Hui Xing, Chong Zhang*, Qiang Fei*, Empowering a Methanol-Dependent Escherichia coli via Adaptive Evolution Using a High-Throughput Microbial Microdroplet Culture System. Frontiers in Bioengineering and Biotechnology, 8: 570 (2020)
24. 张会敏，王艳丽，孟雅静，李安军，周庆伍，胡心行，刘国英，李兰，黄艳，邢新会*, 浓香型白酒新、老窖池池壁泥与池底泥原核菌群结构分析。食品科学， 41(18): 180-187 (2020)
25. 张会敏，王艳丽，孟雅静，王银辉，李安军，王志强，张治洲，邢新会*， 浓香型白酒发酵新老窖泥理化因子和原核微生物群落结构差异分析. 食品科学, 41(6): 207-214 (2020)
26. 袁姚梦, 邢新会, 张翀*，微生物细胞工厂的设计构建：从诱变育种到全基因组定制化创制。合成生物学，1(6): 656-673（2020）
27. 郭肖杰，王立言，张翀*，邢新会*，高通量自动化微生物微液滴进化培养与筛选技术及其装备化。生物工程学报，37(3)，991-1003（2021）
28. Jun-Yu Liu, Dong He, Yi-Fan Xing, Wen Zeng, Kai Ren, Chong Zhang, Yuan Lu, Song Yang, Shu-Jian Ou, Yi Wang *, Xin-Hui Xing*, Effects of bioactive components of Pu-erh tea on gut microbiomes and health: A review. Food Chemistry, 353, 129439 (2021)
29. Yifan XING, Junyu LIU, Xiaojie GUO, Haipeng LIU, Wen ZENG, Yi WANG, Chong ZHANG, Yuan LU, Dong HE, Shaohua Ma, Yonghong He, Xin-Hui XING*, Engineering organoid microfluidic system for biomedicine and health engineering: a review. Chinese Journal of Chemical Engineering, 30, 244-254 (2021)
30. Xiao-Jie Yuan, Wen-Jing Chen, Zeng-Xin Ma, Qian-Qian Yuan, Min Zhang, Lian He, Xu-Hua Mo, Chong Zhang, Chang-Tai Zhang, Meng-Ying Wang, Xin-Hui Xing and Song Yang* Rewiring the native methanol assimilation metabolism by incorporating the heterologous ribulose monophosphate cycle into Methylorubrum extorquens. Metabolic Engineering, 64, 95-110 (2021)
31. Yuting Li＃, Dong He＃, Bing Li, Marianne N. Lund, YifanXing, Yi Wang, Fuxiang Li, Xiao Cao, Yujia Liu, Xiangyu Chen, Jiamei Yu, Jie Zhu, Minlian Zhang, Qiang Wang, Yuhao Zhang, Bin Li, Jinshui Wang, Xin-Hui Xing* and Lin Li*, Engineering polyphenols with biological functions via polyphenol-protein interactions as additives for functional foods. Trends in Food Science & Technology, 110, 470–482 (2021)
32. Yuting Huang#, Liyang Wang#, Xue Zhang, Nan Su, Heping Li, Yoshimitsu Oda, Xinhui Xing*, Quantitative evaluation of DNA damage caused by Atmospheric and Room-Temperature Plasma (ARTP) and other mutagenesis methods using a rapid umu-microplate test protocol for microbial mutation breeding. Journal of Chemical Engineering, in press (2021)
33. Wen Zeng, Dong He, Yifan Xing, Junyu Liu, Nan Su, Chong Zhang, Yi Wang*, Xinhui Xing*, Internal connections between dietary intake and gut microbiota homeostasis in disease progression of ulcerative colitis: a review. Food Science and Human Wellness, 10, 119-130 (2021)
34. Zeng-xin Ma, Min Zhang, Chang-tai Zhang, Hui Zhang, Xu-hua Mo, Xin-hui Xing, Song Yang*, Metabolomic analysis improves bioconversion of methanol to isobutanol in Methylorubrum extorquens AM1. Biotechnology Journal, e2000413 (2021)
35. Chenqi Niu, Chuyi Wang, Fan Li, Xiang Zheng, Xinhui Xing, Chong Zhang*, Aptamer assisted CRISPR-Cas12a strategy for small molecule diagnostics. Biosensors and Bioelectronics, 183, 113196 (2021)
36. Yinan Wu, Aysha Jameel, Xin-Hui Xing and Chong Zhang*, Advanced strategies and tools to facilitate and streamline microbial adaptive laboratory evolution. Trends in Biotechnology, in press (2021)
37. Xi Wu*, Chong Zhang, Xin-Hui Xing, Zhenyu Yun, Lin Zhao, Qi Wu, Construction and characterization of novel bifunctional fusion proteins composed of alcohol dehydrogenase and NADH oxidase with efficient oxidized cofactor regeneration. Biotechnology and Applied Biochemistry, 1-10 (2021)
38. Huibao Feng#, Yaomeng Yuan#, Zheng Yang, Xin-hui Xing, and Chong Zhang*, Genome-wide genotype-phenotype associations in microbes. Journal of Bioscience and Bioengineering, 132 (1), 1-8 (2021)
39. Huibao Feng#, Jiahui Guo#, Tianmin Wang#*, Chong Zhang* and Xin-hui Xing, Guide-target mismatch effects on dCas9–sgRNA binding activity in living bacterial cells. Nucleic Acids Research, 49 (3), 1263–1277 (2021)
40. 张卉，袁姚梦，张翀，杨松*，邢新会*.合成甲基营养细胞工厂同化甲醇的研究进展及未来展望. 合成生物学，2(2): 222-233 （2021）
41. 王彦珺，李姝承，关长阁，何东，廖锡豪，王怡，陈海红，张翀，邢新会*，天然活性多肽的发掘策略和生产技术。生物工程学报， 37(6)，1-15（2021）
42. 苏楠，吴亦楠，陈韵亿，金丽华，张翀，Shimpei Aikawa，Tomohisa Hasunuma，Akihiko Kondo，邢新会*，ARTP 诱变钝顶螺旋藻突变体比较组学研究。化工学报，72(12)，6298-6310（2021）
43. Yi Wu#, Dong He#, Minhua Zong, Hong Wu, Lin Li, Xia Zhang, Xinhui Xing* and Bing Li*, Improvement in the stability and bioavailability of trans-resveratrol with hydrolyzed wheat starch complexation: a theoretical and experimental study. Food Structure, 32, 100267 (2022)
● 学术荣誉与奖励
1993年 日本财团法人手岛工业教育基金团研究纪念奖
2002年 清华大学第五届“良师益友”荣誉称号
2004年 日本竹田国际交流（生物工程领域）贡献奖
2007年 第17届全国发明展览会奖银奖
2008年 北京市科学技术奖三等奖
2009年 中国石油和化学工业协会技术发明奖二等奖
2010年 中国侨界贡献奖（创新人才）和首都新侨乡创新发展先进个人称号
2012年 中国食品产业产学研创新发展“杰出科研人才领军人物奖”
2017年 日内瓦国际发明博览会金奖
2017年 中国化工学会系统2012-2017年度先进个人
2018年 日本东京大学工学院会士（Fellow，School of Engineering, The University of Tokyo）、全国归侨侨眷先进个人
2019年 国际生物过程学会（IBA）会士奖（Fellow Award）、东京工业大学会士（Fellow）和中国轻工业联合会技术发明一等奖
2020年 中国生物发酵产业协会“协同创新精英奖”
2021年 创新肇庆”科学技术奖特等奖
● 实验室主页