报告题目：Engineering an expanded chemical palette in cells
报 告 人：Hal Alper 教授 美国得克萨斯大学奥斯汀分校 (The University of Texas at Austin)
报告时间：2020年4月22日 周三上午9:00-10:00
报告在线地址：腾讯会议（会议ID: 833 079 932）

报告摘要：

An industrial biotechnology revolution is approaching. Recent technical advances are leading to a rapid transformation of the chemical palette available in cells making it conceivable to produce nearly any organic molecule of interest—from biofuels to biopolymers to pharmaceuticals. However, these feats require the ability to “hijack” native cellular machinery and metabolism and navigate the complexity inherent in cellular regulation. In this regard, this talk will describe recent advances in engineering various yeasts for the production of important products, such as organic acids and oleochemicals, with a focus on the synthetic biology tools and directed evolution paradigms required along the way. Collectively, these case studies demonstrate the power and utility of using yeasts as a production host for chemicals.

报告人简介：

Dr. Hal Alper is the Z.D. Bonner Professor of Chemical Engineering and Associate Department Chair at The University of Texas at Austin. He earned his Ph.D. in Chemical Engineering from the Massachusetts Institute of Technology in 2006 and was a postdoctoral research associate at the Whitehead Institute for Biomedical Research from 2006-2008, and at Shire Human Genetic Therapies from 2007-2008. He is currently the Principal Investigator of the Laboratory for Cellular and Metabolic Engineering at The University of Texas at Austin where his lab focuses on metabolic and cellular engineering in the context of biofuel, biochemical, and biopharmaceutical production in an array of model host organisms. Dr. Alper has published over 115 articles and 8 book chapters and is the recipient of the Camille and Henry Dreyfus New Faculty Award in 2008, the Texas Exes Teaching Award in 2009, the DuPont Young Investigator Award in 2010, the Office of Naval Research Young Investigator Award in 2011, the UT Regents’ Outstanding Teaching Award in 2012, the 2013 Biotechnology and Bioengineering Daniel I.C. Wang Award, the Jay Bailey Young Investigator Award in Metabolic Engineering in 2014, the 2014 Camille Dreyfus Teacher-Scholar Award, 2015 Society for Industrial Microbiology and Biotechnology Young Investigator Award, 2016 ACS BIOT Young Investigator Award, 2016 UT-Austin Emerging Inventor of the Year Award, and 2018 AIChE Allan P. Colburn Award for Excellence in Publications by a Young Member of the Institute. He was recently inducted as a Fellow of both the National Academy of Inventors The American Institute for Medical and Biological Engineering.