主要从事生物化工领域的教学和研究工作。发表论文210篇，其中SCI收录 130篇，他引2500余次，授权发明专利12项。培养研究生逾50名，其中全国优秀百篇博士论文1人。获得全国高等学校优秀骨干教师奖（2002），国务院政府特殊津贴（2007），全国优秀博士论文指导教师（2008），宝钢全国优秀教师奖特等奖提名奖（2016），2012年入选教育部长江学者特聘教授。
● 教育与工作经历
1982-1987，清华大学化学工程系，本科
1987-1989，清华大学化学工程系，硕士
1989-1993，清华大学化学工程系，博士
1993-1994，日本东京工业大学生命理工学部，UNESCO Fellow
1989-目前， 清华大学化学工程系，1998年晋升为教授
● 研究领域
1）蛋白质构象转化与调控及其在生物分离的应用
2）固定化酶技术及应用
3）微生态构建与调控及其在土壤生物修复和大健康领域中的应用
● 主要学术任职
教育部化工类教学指导委员会 委员
中国化工学会生物化工专业委员会 副主任
生化工程国家重点实验室学术委员会 委员
ACS Industrial Engineering & Chemistry Research 顾问编委
Chinese Journal of Chemical Engineering, 华东理工大学学报 编委
● 代表性论文
1. Meng Xia, Zheyu Wang, Linhan Du, Zhongwang Fu, Guoqiang Jiang, Diannan Lu, Jianzhong Wu, and Zheng Liu, A Core-Shell Cascade of Chloroperoxidase and Gold Nanoclusters for Asymmetric Hydroxylation of Ethylbenzene, ChemCatChem, 2022, e202101732，DOI:10.1002/cctc.202101732
2. Zheyu Wang, Yupei Jian, Yilei Han, Zhongwang Fu, Diannan Lu, Jianzhong Wu*, Zheng Liu,* Recent progress in enzymatic functionalization of carbon-hydrogen bonds for the green synthesis of chemicals, Chinese J. Chem. Eng., 2020, 28, 2499–2506 https://doi.org/10.1016/j.cjche.2020.06.040
3. Weina Xu, Zhongwang Fu, Gong Chen, Zheyu Wang, Yupei Jian, Yifei Zhang, Guoqiang Jiang, Diannan Lu, Jianzhong Wu and Zheng Liu*, Graphene oxide enabled long-term enzymatic transesterification in an anhydrous gas flux, Nature Communications, 2019, 10:2684, DOI: 10.1038/s41467-019-10686-z
4. Zheyu Wang, Junqian Wang, Gong Chen, Weina Xu, Zhongwang Fu, Guoqiang Jiang, Jianzhong Wu and Zheng Liu*, Polyelectrolytes tailored enzyme cascades with enhanced stability and activity for one-pot synthesis, ChemCatChem, 2018, 10, 5391-5396 DOI: 10.1002/cctc.201801532
5. Gong Chen, Diannan Lu,* Jianzhong Wu and Zheng Liu*,Detachment of HCO3− from the Active Site of Carbonic Anhydrase: Molecular Dynamics Simulation and Machine Learning, J. Phys. Chem. C 2018, 122, 20539−20549 DOI:10.1021/acs.jpcc.8b05298
6. Gong Chen, Xian Kong, Diannan Lu, * Jianzhong Wu* and Zheng Liu*，Kinetics of CO2 diffusion in human carbonic anhydrase: a study using molecular dynamics simulations and the Markov-state model，Phys. Chem. Chem. Phys., 2017, 19, 11690-11697
7. Yifei Zhang, You Yong, Jun Ge, and Zheng Liu*, Lectin agglutinated multienzyme catalyst with enhanced substrate affinity and activity, ACS Catal. 2016, 6, 3789-3795.
8. Yifei Zhang, Jun Ge,* and Zheng Liu*, Enhanced Activity of Immobilized or Chemically Modified Enzymes, ACS Catal. 2015, 5, 4503-4513.
9. Xian Kong, Diannan Lu*, Zheng Liu* and Jianzhong Wu*, Molecular dynamics for the charging behavior of nanostructured electric double layer capacitors containing room temperature ionic liquids, Nano Research, 2015, 8, 931-940.
10. Yijie Dong, Zhe Lang, Xian Kong, Dianan Lu* and Zheng Liu*, Kinetic and multidimensional profiling of accelerated degradation of oil sludge by biostimulation. Environmental science. Processes & impacts , 2015, 17, 763-774.
11. Yifei Zhang, Fengjiao Lyu, Jun Ge* and Zheng Liu*, Ink-jet printing an optimal multi-enzyme system, Chem. Commun., 2014, 50, 12919-12922.
12. Zhixian Li, Yifei Zhang, Yechao Su, Pingkai Ouyang, Jun Ge* and Zheng Liu*, Spatial co-localization of multi-enzymes by inorganic nanocrystal–protein complexes, Chem. Commun., 2014, 50, 12465-12468.
13. Rui Wang, Yifei Zhang, Jinhai Huang, Jun Ge*, and Zheng Liu*, Substrate imprinted lipase nanogel for one-step synthesis of chloramphenicol palmitate , Green Chem. 2013, 15:1155-1158.
14. Yifei Zhang, Qile Chen, Jun Ge* and Zheng Liu*,Controlled display of enzyme activity with a stretchable hydrogel, Chem. Commun., 2013, 49, 9815-9817.
15. Jingying Zhu, YifeiZhang, Diannan Lu, RN Zare, Jun Ge* and Zheng Liu*, Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media, Chem. Commun., 2013, 49, 6090-6092.
16. MM Lin, DN Lu, C. Yang, JY Zhu, YF Zhang, and Z Liu*, Magnetic enzyme nanogels (MENGs): a universal synthetic route for biocatalysts. Chem. Commun., 2012, 48, 3315-3317.
17. Cheng Yang, Diannan Lu, and Zheng Liu*, How PEGylation Enhances the Stability and Potency of Insulin: A Molecular Dynamics Simulation, Biochemistry 2011, 50, 2585-2593.
18. Ming Yan, Juanjuan Du, Zhen Gu, Min Liang, Yufang Hu, Wenjun Zhang, Saul Priceman, Lily Wu, Hong Z Zhou, Zheng Liu*, Tatiana Segura*, Yi Tang* and Yunfeng Lu*, A novel intracellular protein delivery platform based on single-protein nanocapsules. Nat. Nanotech., 2010, 5, 1, 48-53.
19. Jun Ge, Diannan Lu, Jun Wang, and Zheng Liu*, Lipase Nanogel Catalyzed transesterification in Anhydrous Dimethyl Sulfoxide, Biomacromolecules, 2009, 10, 1612-1618.
20. Ming Yan, Jun Ge, Zheng Liu*, Pingkai Ouyang, Encapsulation of Single Enzyme in Nanogel with Enhanced Biocatalytic Activity and Stability, J. Am. Chem. Soc., 2006, 128, 11008-11009.